ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or continue ADHD medications during breastfeeding and pregnancy is a challenge for women suffering from the condition. There are few data regarding how exposure over time may affect the fetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication in utero do not develop neurological developmental conditions like hearing or vision impairment seizures, febrile seizures, or IQ impairment. The authors acknowledge the need for higher-quality studies.
Risk/Benefit Analysis
Women who are expecting and taking ADHD medication must consider the benefits of taking it versus the risks to the baby. Physicians do not have the information needed to give clear guidelines, but they can provide information regarding benefits and risks that can aid pregnant women in making informed decisions.
A study published in Molecular Psychiatry concluded that women who were taking ADHD medication in early pregnancy did not have a higher risk of fetal malformations or structural birth defects. Researchers conducted a large population-based study of case control to assess the frequency of major structural defects in infants who were born to mothers who took stimulants during pregnancy. Clinical geneticists and pediatric cardiologists examined the cases to ensure correct case classification and to limit the possibility of bias.
However, the researchers’ study had its limitations. In particular, they were unable to separate the effects of the medication from the underlying disorder. This makes it difficult for researchers to determine if the few associations observed between the exposed groups were due to the use of medication or confounded by the presence of comorbidities. Additionally the study did not examine long-term offspring outcomes.
The study did reveal that infants whose mothers had taken ADHD medications during pregnancy were at a slightly higher risk of being admitted to the neonatal intensive care unit (NICU) than infants who whose mothers did not take any medication or had cut back on their medications prior to or during pregnancy. This was due to central nervous system-related disorders and the increased risk for admission did not appear to be influenced by the stimulant medications were used during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher likelihood of having to have a caesarean section or a baby that scored low on the Apgar scale (less than 7). These increases didn’t appear to be influenced by the kind of medication used during pregnancy.
Researchers suggest that the small risk of using ADHD medications during early pregnancies could be offset by the greater benefits for baby and mother of continued treatment for the woman’s disorder. Physicians should discuss the issue with their patients and, if possible, help them develop strategies to improve their coping abilities which can reduce the impact of her disorder on her daily life and relationships.
Medication Interactions
Many doctors are confronted with the dilemma of whether to continue treatment or stop it during pregnancy as more women are diagnosed with ADHD. The majority of these decisions are made in the absence of clear and authoritative evidence either way, so physicians must weigh what they know from their own experiences, those of other doctors, and what the research says on the topic, along with their own best judgment for each individual patient.
The issue of potential risks to infants is extremely difficult. The research on this issue is based on observations rather than controlled studies and a lot of the results are conflicting. Most studies limit their analysis to live births, which may underestimate the severity of teratogenic effects that can a general physician prescribe adhd medication lead to terminations or abortions of pregnancy. The study discussed in the journal club addresses these issues by analyzing the data from deceased and live births.
The conclusion: While some studies have found a positive association between ADHD medications and the risk of certain birth defects, others have found no connection and the majority of studies show a neutral or even slight negative effect. In all cases, a careful study of the benefits and risks must be performed.
It isn’t easy, but not impossible for women suffering from ADHD to stop taking their medication. In a recent article in the Archives of Women’s Mental Health psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can lead to increased depression, feelings of loneliness and family conflict for those suffering from the disorder. In addition, a decrease in medication can affect the ability to do jobs and drive safely that are crucial aspects of daily life for many people with ADHD.
She recommends women who are unsure about whether to keep or stop medication for inattentive adhd in light of their pregnancy should consider educating family members, friends, and coworkers on the condition, its impact on daily life, and the advantages of continuing the current treatment regimen. It can also help a woman feel confident about her decision. It is also worth noting that certain medications can be absorbed through the placenta therefore, if a patient decides to stop taking her ADHD medication during pregnancy and breastfeeding, she should be aware that the effects of the drug could be transferred to the child.
Risk of Birth Defects
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) increases there are concerns about what impact the drugs could have on foetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge on this issue. Researchers utilized two massive datasets to analyze more than 4.3 million pregnancy and determine if the use of stimulant medications increased the risk of birth defects. Researchers discovered that although the risk overall is low, first-trimester ADHD medication use was associated with slightly higher rates of specific heart defects like ventriculoseptal defects.
The researchers of the study did not discover any connection between early medication usage and other congenital anomalies, like facial deformities or club feet. The results are consistent with previous studies revealing a small but significant increase in the risk of cardiac malformations among women who started taking ADHD medications prior to pregnancy. This risk increased during the latter half of pregnancy when a large number of women began to stop taking their medication.
Women who took adhd medication private prescription medication during the first trimester were more likely to require a caesarean delivery or have an insufficient Apgar after delivery, and had a baby that required breathing assistance when they were born. The researchers of the study could not eliminate bias due to selection because they limited their study to women who did not have any other medical conditions that might have contributed to the findings.
Researchers hope that their study will inform physicians when they see pregnant women. They advise that while a discussion of the risks and benefits is crucial but the decision to stop or continue medication must be based on each woman’s needs and the severity of her ADHD symptoms.
The authors also caution that even though stopping adhd medication weekends adults the medication is an option, it is not a recommended practice because of the high incidence of depression and other mental health problems in women who are pregnant or recently post-partum. Research has also shown that women who stop taking their medication will have a harder time adjusting to a life without them once the baby is born.
Nursing
It can be a stressful experience to become a mother. Women who suffer from ADHD can face severe challenges when they must deal with their symptoms, go to doctor appointments and prepare for the birth of their child and adjust to a new routine. Many women opt to continue taking their ADHD medication during pregnancy.
The risk to breastfeeding infant is minimal because the majority of stimulant medications is absorbed through breast milk in low amounts. The rate of medication exposure will vary based on the dosage and frequency of administration as well as the time of the day. Additionally, different medications enter the baby’s system via the gastrointestinal tract or through breast milk. The impact of these medications on the health of a newborn isn’t completely known.
Some physicians may discontinue stimulant medications during a woman’s pregnancy due to the lack of research. This is a difficult choice for the patient, who must weigh the benefits of keeping her medication with the potential risks to the fetus. As long as more information is available, GPs may ask pregnant patients whether they have any background of ADHD or if they intend to take medication in the perinatal phase.
Numerous studies have proven that women can continue to take their ADHD medication safely during pregnancy and while breast-feeding. As a result, an increasing number of patients choose to do so and, in consultation with their physician, they have discovered that the benefits of continuing their current medication exceed any risk.
Women who suffer from Strongest Adhd Medication For Adults who plan to breastfeed should seek advice from a specialist psychiatrist before becoming pregnant. They should review their medications with their doctor and discuss the pros and cons of continued treatment, including non medication treatment for adhd-pharmacological strategies. Psychoeducation is also required to help pregnant women suffering from ADHD recognize the signs and the underlying disorder. They should also be informed about treatment options and reinforce strategies for coping. This should be a multidisciplinary effort including obstetricians, GPs and psychiatry. The pregnancy counselling should consist of the discussion of a treatment plan for both the mother as well as the child, as well as monitoring for signs of deterioration and when necessary, making adjustments to the medication regimen.