Mesothelioma and Asbestos
Asbestos, a mineral that naturally forms in the form of long, thin fibers. People who are exposed to asbestos on a regular basis are at risk of developing mesothelioma as well as other lung diseases of different types.
The symptoms of these diseases might not manifest for years after exposure to asbestos. Different asbestos types can cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma occurs in the lung’s outer lining, or the pleura. It is the most common mesothelioma type and accounts for 70% to 79% of diagnosed cases. The condition can cause chest pain, shortness of breathe and a feeling heavyness.
Exposure to asbestos, a group of minerals composed of microscopic fibers, usually causes this type of cancer. The fibers, when inhaled can cause irritation and DNA mutations. The pleura surrounds the lungs and chest cavity, so these irritations can affect both the lungs as well as the heart of a person. Mesothelioma symptoms usually don’t appear until 30 to 50 years after exposure.
Chest pain and shortness breath are the most frequent symptoms. Some patients have coughing problems, trouble breathing, or chest tightness. People with this cancer have a past that includes asbestos exposure at work. Construction, manufacturing and shipbuilding are among the most frequent occupations which put people at risk risk of developing pleural mesothelioma. People who have served in the military could be at an especially high risk due to the frequent asbestos usage in Navy vessels and bunkers for the army.
The most common staging method for pleural mesothelioma is the TNM (tumor lymph nodes, lymph nodes and metastases) staging system. The stage a patient is in when they are diagnosed will help their doctor determine the best treatment plan for them. For instance, patients suffering from a pleural mesothelioma in stage three or four have a less favorable prognosis than those in lower stages. Mesothelioma in stage four is usually spread to the diaphragm, liver or even the heart of a patient. This can make it more difficult to treat and increases the likelihood of complications for the patient.
Peritoneal Mesothelioma
Unlike pleural mesothelioma, which is a lung-lining cancer, peritoneal mesothelioma develops in the peritoneum, an elongated membrane that covers the abdominal cavity and organs like the intestines and the liver. Similar to pleural mesothelioma, exposure to asbestos is the cause of peritoneal mesothelioma. The disease is less prevalent than pleural mesothelioma. There are just 300-500 cases being diagnosed each year.
As with pleural asbestosis, symptoms can take several years to manifest. The majority of patients are afflicted with abdominal pain as well as abdominal swelling. The symptoms of this type of mesothelioma could also include nausea or weight loss, as well as fever. Many of these symptoms could be misinterpreted as gastrointestinal issues and can lead to a misdiagnosis.
Generally, doctors can find mesothelioma after a thorough health history and physical examination. Imaging tests such as X-rays or CT scans are a way to detect mesothelioma. These tests can identify tumors and other cancer signs that are not visible on X-rays.
The results of these tests allow doctors to diagnose mesothelioma and determine the stage. They also offer treatments. The stage is determined by the type of cell and whether the tumor has spread.
The most significant risk factor for mesothelioma is exposure to asbestos. People who have worked in jobs that involve Asbestos Legal (Yaksteel6.Werite.Net), such as plumbing, manufacturing, electrical work, or construction, are at a higher risk of developing the disease. Even if a person is not employed in one of these fields they could be exposed to asbestos through family members or other sources. Anyone who thinks they are at risk should consult a doctor. If they have an history of exposure to asbestos and mesothelioma is a concern, a specialist will help them find out more about their risk.
Risk Factors
Asbestos is the primary risk factor in mesothelioma. It is responsible for up to 80percent of cases. Exposure to asbestos can happen as a result of work, military service, or through living with a person who is exposed to asbestos or was previously exposed to doing so. When exposed to asbestos, small particles can be breathed into the lungs and abdomen. They can cause irritation to the linings of the abdomen and cause cancerous cells to develop in the mesothelium. Mesothelioma can take between 15 and 60 years to develop after exposure to asbestos.
Other risk factors include smoking, genetics and age. People in their 40s and 50s are more at risk of developing mesothelioma as compared to people who are younger or more. It takes mesothelioma between 20 and 60 years to manifest cancer symptoms after the first exposure. It is important to note that mesothelioma may develop in those who have been exposed to asbestos attorney, but without having worked with it directly. This is called indirect or secondary exposure to asbestos. It can be just as dangerous as direct exposure.
Smoking can increase the likelihood of developing mesothelioma due to the fact that it damages the mesothelium and makes it more prone to asbestos litigation. Furthermore, mesothelioma is exacerbated by certain illnesses like pneumonia and asbestosis. Men are more likely to develop mesothelioma compared to women. This is because men are more likely to work with asbestos and experience a an extended period of exposure than women. Men are also more likely to live with someone who worked with asbestos and carry stray asbestos fibers home on their clothing. Women are less likely to be in contact with asbestos, and they don’t usually carry asbestos on their clothes.
Diagnosis
Mesothelioma is a difficult cancer to diagnose because the symptoms often resemble other conditions. This can result in patients being misdiagnosed.
NYU Langone doctors will perform a physical examination and record the patient’s medical background, including asbestos exposure. Doctors will also order a CT scan or chest X-ray in order to look for lumps, abnormalities, and evidence of asbestos settlement exposure. These include plaques on the pleura, pleura that are thickened and calcium deposits.
Other diagnostic tests include an echocardiogram, which examines the blood vessels and the heart, and a magnetic resonance imaging, or MRI test, which uses magnets and radio waves to create precise images of the inside of the body. A surgical biopsy is a different way for doctors to diagnose mesothelioma. When a biopsy is performed doctors take a tiny piece of tissue from the pleura or the peritoneum, to be examined further. A pathologist can look at the tissue under microscopes to determine if it has cancerous cells.
Mesothelioma can be classified based on the type of mesothelial cell involved, whether those cells are malignant or benign and also the location of the tumor, the type, and the stage of the tumor. Certain types of mesothelioma are at a higher risk of metastasizing or spreading and it’s crucial to get a definitive diagnosis so doctors can treat it before it becomes out of control.
Doctors can also run tests in the lab on a tumor to identify specific proteins, genes or other elements that help them understand the cancer’s characteristics and plan treatment. These results are referred to as staging.
Treatment
A diagnosis of mesothelioma can be an incredibly frightening prospect. However, it is important to remember that the cancer is treatable, especially in its earlier stages. Many patients with mesothelioma endure the disease for a long time, without spreading.
Asbestos exposure can cause mesothelioma through many mechanisms. Asbestos fibers, which are too small to see or feel with the naked eye, can become airborne and irritate the lining of the lungs (pleura). Over time irritation leads to formation of scar tissue which can cause changes in the cell structure that can eventually grow into tumors.
The pleura is a protective covering that surrounds the lungs, heart and abdomen. Mesothelium is made up of cells that respond when exposed to asbestos. They cause inflammation to the tissue and cause it to become scarred. In time, these changes can result in the growth of malignant mesothelioma tumors.
The signs of pleural mesothelioma can include breathing problems and chest pain as well as a buildup of fluid in the lungs (pleural effusion). In rare instances, the cancer can spread to the tissues surrounding the heart and reproductive organs.
A doctor will order biopsy if scans show a potential tumor in the lungs or stomach. During the procedure, doctors remove tiny amounts of fluid or tumor for lab analysis. The results will confirm a mesothelioma diagnosis, and determine the best treatment plan.
There are a variety of treatment for mesothelioma including surgery and chemotherapy. Most doctors use a combination of these treatments. Patients may also benefit from taking part in a clinical trial of new mesothelioma therapies. To find out more, patients should speak to mesothelioma experts who have experience treating the condition.